You are searching about Which Of The Following Hereditary Diseases Involves Multiple Genetic Mutations, today we will share with you article about Which Of The Following Hereditary Diseases Involves Multiple Genetic Mutations was compiled and edited by our team from many sources on the internet. Hope this article on the topic Which Of The Following Hereditary Diseases Involves Multiple Genetic Mutations is useful to you.
Which Of The Following Hereditary Diseases Involves Multiple Genetic Mutations
Leukemia does not usually run in families, so in most cases, it is not hereditary. And while some people inherit genetic features that increase their risk, this does not mean they will develop the condition.Scientists know that genetic changes play a role in the development of leukemia, but not all genetic features are hereditary. Sometimes, a person is born with a genetic feature they have not inherited from their biological parents. This feature developed after conception but before birth. Such features may increase the risk of leukemia.Environmental and lifestyle factors can also affect someone’s genes and increase their risk. These factors include exposure to toxic chemicals and smoking. These types of genetic changes occur during a person’s lifetime, and doctors call them acquired genetic changes.While scientists have identified both acquired and inherited genetic features that occur with leukemia, they have not identified any hereditary gene that causes the disease.In most cases, it is not possible to know why leukemia occurs.This article will explore the links between leukemia, family history, and genetics. We also discuss the risk factors and tips for preventing this condition.Leukemia is a genetic disease but not necessarily inherited.It is a genetic disease because it relates to a person’s DNA, the material that carries genetic information. DNA determines the development, growth, and function of body cells.DNA is responsible for determining unchangeable features, such as eye and hair color, but also the continued growth and development of blood, skin, and other bodily cells.People inherit DNA, but it can also change during gestation before birth or during their lifetime.Leukemia results from changes in the DNA of bone marrow cells. It causes atypical cell development in the blood and bone marrow. Leukemia cells may prevent bone marrow from producing healthy cells.In rare cases, heredity may play a role. Familial acute myeloid leukemia (AML) is an inherited form of AML. People who have familial AML may have altered CEBPA genes.Sometimes, parents pass along certain genetic mutations or inherited conditions that increase a child’s risk of developing leukemia, such as Li-Fraumeni syndrome or Down syndrome. Types of leukemia that may occur alongside other genetic conditions include:However, leukemia-related DNA changes usually develop after conception rather than being inherited from a parent’s genes. Exposure to radiation, chemicals, infections, and other environmental factors contribute to genetic changes that result in atypical DNA.However, in most cases, doctors do not know why leukemia occurs.Learn more about AML genetic mutations.Risk factors that increase a person’s chances of developing leukemia include:Genetic featuresLeukemia is a genetic disease that results from changes in a person’s genes. People can inherit genetic risk factors, or their genes can change because of environmental triggers.The authors of a 2019 study found that certain gene mutations, specifically FLT3-ITD and NRAS mutations, frequently appear in people with AML-M5, a type of AML that forms in immature white blood cells.Family historyInherited forms of leukemia appear to be rare. However, some subtypes of the following leukemias may be due to inherited genetic features:There may be another inherited condition in the family with the same genetic change, such as a platelet deficiency or immune condition. AgeOne form of leukemia, ALL, is more common among children and teenagers than adults.The risk of developing ALL is higher during childhood but falls as people enter their 20s. It rises again after the age of 50 years.The risk of developing most cancers increases with age. The American Cancer Society (ACS) estimates that 9 out of 10 people with CLL are aged 50 years or older. SexMales are slightly more likely to have CLL than females. ALL also occurs more often in males than females.RaceThe ACS notes that leukemia is more common in white Americans than in Black Americans. However, research suggests Black people may face poorer prognoses due to disparities in access to care, diagnosis, and treatment.How do racial disparities affect cancer rates and treatment for Black Americans?Other inherited genetic disordersThe ACS states that the following inherited genetic syndromes may increase the risk of ALL:Environmental exposuresExposure to environmental factors can increase the risk. Here are some factors that appear to contribute to leukemia:toxic substances, such as benzeneradiation, for example, during a nuclear accident, radiation therapy, or X-ray imagingchemotherapyBenzene is a chemical present in many products, including gasoline, glue, cleaning supplies, cigarettes, detergents, and dyes. According to the CDC (Centers for Disease Control and Prevention), benzene is in the top 20 most produced chemicals in the United States.What is the link between benzene and leukemia?In most cases, it is not clear why leukemia develops. However, being aware of the risk factors can help people take precautions.Here are some tips for reducing the risk:learn about risks that have links to known genetic features in the familyavoid or quit smokingavoid contact with benzene, formaldehyde, and other toxic chemicalsHere are some questions people often ask about leukemia and heredity.What kind of leukemia is hereditary?In rare cases, people inherit genetic traits that increase their risk of leukemia, but it does not mean they will develop it. Scientists have found genetic links to various types of this disease. However, most genetic changes that increase the risk happen during a person’s lifetime.Who is more likely to get leukemia?Most cases of leukemia do not have an obvious cause, but exposure to high levels of radiation and certain toxins can increase the risk. It can also occur in people with a history of radiation therapy and chemotherapy and in those with certain genetic conditions, such as Down syndrome and Fanconi anemia.Is there genetic testing for leukemia?Genetic testing can show doctors which kind of genetic changes are present in cancer cells, and this can help identify the type of leukemia. However, it cannot show if someone is likely to inherit or pass on the disease. In most cases, the genetic changes that occur with leukemia are not hereditary.Leukemia involves atypical cell development in the blood and bone marrow. It does not usually run in families, but people can inherit genetic features that increase their risk of developing it.It is not always possible to prevent leukemia, but taking steps, such as avoiding smoking and exposure to certain toxins, may help.
Video about Which Of The Following Hereditary Diseases Involves Multiple Genetic Mutations
Genetic Diseases: Categories – Genetics | Lecturio
This video “Genetic Diseases: Categories” is part of the Lecturio course “Genetics” ► WATCH the complete course on http://lectur.io/geneticdiseasescategories
► LEARN ABOUT:
– Categories of Genetic Diseases
– Chromosome disorders
– Single-gene disorders
– Multifactorial disorders
► THE PROF:
Dr. Georgina Cornwall has taught a broad array of Biology courses at different U.S. universities, currently at the Colorado Mountain College in Aspen. Dr. Cornwall is an active promoter of hybrid teaching formats like online and interactive courses. Thus, she uses modern technology to engage her students in the diverse disciplines of biology – from Microbiology to Genetics.
► LECTURIO is your single-point resource for medical school:
Study for your classes, USMLE Step 1, USMLE Step 2, MCAT or MBBS with video lectures by world-class professors, recall & USMLE-style questions and textbook articles. Create your free account now: http://lectur.io/geneticdiseasescategories
► INSTALL our free Lecturio app
iTunes Store: https://app.adjust.com/z21zrf
Play Store: https://app.adjust.com/b01fak
► READ TEXTBOOK ARTICLES related to this video:
Human Genetics – Chromosomal Aberrations
► SUBSCRIBE to our YouTube channel: http://lectur.io/subscribe
► WATCH MORE ON YOUTUBE: http://lectur.io/playlists
► LET’S CONNECT:
• Facebook: https://www.facebook.com/lecturio.medical.education.videos
• Instagram: https://www.instagram.com/lecturio_medical_videos
• Twitter: https://twitter.com/LecturioMed
Question about Which Of The Following Hereditary Diseases Involves Multiple Genetic Mutations
If you have any questions about Which Of The Following Hereditary Diseases Involves Multiple Genetic Mutations, please let us know, all your questions or suggestions will help us improve in the following articles!
The article Which Of The Following Hereditary Diseases Involves Multiple Genetic Mutations was compiled by me and my team from many sources. If you find the article Which Of The Following Hereditary Diseases Involves Multiple Genetic Mutations helpful to you, please support the team Like or Share!
Rate Articles Which Of The Following Hereditary Diseases Involves Multiple Genetic Mutations
Rate: 4-5 stars
Search keywords Which Of The Following Hereditary Diseases Involves Multiple Genetic Mutations
Which Of The Following Hereditary Diseases Involves Multiple Genetic Mutations
way Which Of The Following Hereditary Diseases Involves Multiple Genetic Mutations
tutorial Which Of The Following Hereditary Diseases Involves Multiple Genetic Mutations
Which Of The Following Hereditary Diseases Involves Multiple Genetic Mutations free