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Which Drug Below Is Approved For Chronic Idiopathic Constipation

Trulance can cause mild or serious side effects. The following lists contain some of the key side effects that may occur while taking Trulance. These lists do not include all possible side effects.For more information about the possible side effects of Trulance, talk with your doctor or pharmacist. They can give you tips on how to manage any side effects that may be concerning or bothersome.Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. If you would like to notify the FDA about a side effect you’ve had with Trulance, you can do so through MedWatch.Mild side effectsMild side effects* of Trulance can include:Most of these side effects may go away within a few days or a couple of weeks. But if they become more severe or don’t go away, talk with your doctor or pharmacist. * This is a partial list of mild side effects from Trulance. To learn about other mild side effects, talk with your doctor or pharmacist, or view Trulance’s prescribing information.† For more information about this side effect, see “Side effect details” below. Serious side effectsSerious side effects from Trulance aren’t common, but they can occur. Call your doctor right away if you have serious side effects. Call 911 or your local emergency number if your symptoms feel life threatening or if you think you’re having a medical emergency.Serious side effects* of Trulance can include: * For more information about these side effects, see “Side effect details” below.† Trulance has a boxed warning for this side effect in children. This is the most serious warning from the Food and Drug Administration (FDA). Side effect detailsHere are some details on certain side effects this drug may cause. To find out how often side effects occurred in clinical trials, see the prescribing information for Trulance.DiarrheaMild diarrhea is the most common side effect of Trulance. With mild diarrhea, you may have loose stools along with other symptoms such as abdominal pain, bloating, or cramps. In clinical trials, mild diarrhea typically happened within the first 4 weeks of starting Trulance treatment.In rare cases, Trulance may cause severe diarrhea. With severe diarrhea, your symptoms may be so serious that your condition needs to be treated in a hospital. In the clinical trials, severe diarrhea typically happened within the first 3 days of starting Trulance treatment.Both mild and severe diarrhea can increase your risk of dehydration.* With dehydration, your body loses large amounts of water and electrolytes (essential minerals that are found in your body).* Trulance has a boxed warning for this side effect in children. This is the most serious warning from the Food and Drug Administration (FDA).Steps you can takeIf you have diarrhea, you can stay hydrated by drinking sports drinks or water. Certain foods may also help relieve diarrhea. Examples include bananas, rice, apples, and toast (commonly called the BRAT diet).Talk with your doctor if you have bothersome or severe diarrhea while taking Trulance. They may have you stop taking the drug until your symptoms ease. In severe cases, your doctor may advise you to go to the hospital for IV rehydration (fluids injected into your body through an IV).Risk of serious dehydration in childrenTrulance may cause serious dehydration in children. In fact, Trulance has a boxed warning for this side effect. A boxed warning is the most serious warning from the FDA. It alerts doctors and patients about drug effects that may be dangerous.Animal trials found an increased risk of dehydration in young animals that were given Trulance. But animal trials don’t always predict what will happen in humans. It isn’t known for sure if Trulance increases the risk of dehydration in children.Because of how Trulance works in the body, the drug may increase the risk of severe diarrhea in children younger than age 6 years. And severe diarrhea can lead to serious dehydration.Due to this risk, children younger than age 6 years should not be given Trulance. And doctors typically will not prescribe Trulance for use in people younger than age 18 years. Trulance is not approved for this age group.Your child’s doctor can recommend treatment options for their condition.Allergic reactionAs with most drugs, some people can have an allergic reaction after taking Trulance.Symptoms of a mild allergic reaction can include:A more severe allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include:swelling under your skin, typically in your eyelids, lips, hands, or feetswelling of your tongue, mouth, or throattrouble breathingCall your doctor right away if you have an allergic reaction to Trulance, as the reaction could become severe. Call 911 or your local emergency number if your symptoms feel life threatening or if you think you’re having a medical emergency.

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