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What Is The Difference Between Spiriva Respimat And Stiolto Respimat

Stiolto Respimat can interact with several other medications.Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase the number of side effects or make them more severe.Stiolto Respimat and other medicationsBelow is a list of medications that can interact with Stiolto Respimat. This list doesn’t contain all drugs that may interact with Stiolto Respimat.Before taking Stiolto Respimat, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.Stiolto Respimat and other LABAsTaking Stiolto Respimat with other long-acting beta2-agonists (LABAs) can increase your risk for serious side effects, including heart problems (such as high blood pressure) and even death. This can happen because Stiolto Respimat already contains a LABA as an active drug. So your body would be exposed to too much of the LABAs.Examples of other LABAs include:arformoterol (Brovana)formoterol (Perforomist, Foradil)salmeterol (Serevent)indacaterol (Arcapta)olodaterol (Striverdi)To avoid these interactions, tell your doctor about all chronic obstructive pulmonary disease (COPD) medications you take. They’ll make sure that you’re not taking more than one type of LABA.Stiolto Respimat and theophyllineTaking Stiolto Respimat with theophylline (Theo-24, Theocron) can increase your risk for hypokalemia (low potassium levels). This can lead to serious heart problems such as heart palpitations (the feeling of skipped or extra heartbeats). It can also lead to muscle problems such as spasms (twitches).If you need to take Stiolto Respimat with theophylline, your doctor may monitor your potassium levels.Stiolto Respimat and steroidsTaking Stiolto Respimat with steroids, such as corticosteroids, can increase your risk for hypokalemia (low potassium levels). This can lead to serious heart problems such as heart palpitations (the feeling of skipped or extra heartbeats). It can also lead to muscle problems such as spasms (twitches).Examples of steroids that can lower potassium levels if taken with Stiolto Respimat include:There are many combination medications that also contain a corticosteroid.If you need to take Stiolto Respimat with a steroid, your doctor may monitor your potassium levels.Stiolto Respimat and diureticsTaking Stiolto Respimat with a diuretic (often called a water pill) can increase your risk for hypokalemia (low potassium levels). Diuretics may also interact and cause an abnormal heart rhythm (a heartbeat that’s too fast, too slow, or uneven). This can lead to serious heart problems such as heart palpitations (the feeling of skipped or extra heartbeats). It can also lead to muscle problems such as spasms (twitches).Examples of diuretics that can lower potassium levels if taken with Stiolto Respimat include:There are also many combination blood pressure medications that contain a diuretic.If you need to take Stiolto Respimat with a diuretic, your doctor may monitor your potassium levels.Stiolto Respimat and certain antidepressantsTaking Stiolto Respimat with certain antidepressants can increase your risk for abnormal heart rhythms (a heartbeat that’s too fast, too slow, or uneven). This can lead to serious, potentially fatal, heart problems such as increased blood pressure.Examples of certain antidepressants that can increase the risk of heart problems if taken with Stiolto Respimat include:If you’re taking an antidepressant, be sure to tell your doctor. They may recommend a different antidepressant that won’t interact with Stiolto Respimat.Stiolto Respimat and certain heart rhythm drugsTaking Stiolto Respimat with certain drugs that affect your heart rate can increase your risk for an abnormal heart rhythm (a heartbeat that’s too fast, too slow, or uneven). This can increase your risk for serious, potentially fatal, heart problems such as ventricular arrhythmia (a heart rhythm disorder).Examples of drugs that can increase the risk of abnormal heart rhythms if taken with Stiolto Respimat include:amiodarone (Pacerone, Nexterone)dronedarone (Multaq)dofetilide (Tikosyn)sotalol (Betapace, Sorine, Sotylize)If you need to take Stiolto Respimat with one of these heart rhythm drugs, your doctor will monitor your heart function closely.Stiolto Respimat and certain heart rate or blood pressure medicationsBeta-blockers are medications that treat your heart rate or blood pressure. Taking Stiolto Respimat with certain beta-blockers can prevent Stiolto Respimat from working in your body. This can make Stiolto Respimat less effective. It can also cause your airway muscles to tighten severely.Examples of beta-blockers include:Stiolto Respimat shouldn’t be prescribed with a beta-blocker unless there’s an emergency situation, such as a heart attack. Talk with your doctor if you have any concerns.Stiolto Respimat with certain urinary incontinence medicationsAnticholinergics are medications that treat urinary incontinence (loss of bladder control). Anticholinergics can also treat COPD when they are taken in an inhaler. This includes tiotropium, one of the active drugs in Stiolto Respimat.Taking Stiolto Respimat with other anticholinergics can increase your risk for serious side effects. Some of these side effects include eye problems, such as glaucoma, or urinary problems, such as trouble urinating.Examples of urinary incontinence drugs that can increase the risk of side effects if taken with Stiolto Respimat include:oxybutynin (Ditropan XL)tolterodine (Detrol)darifenacin (Enablex)solifenacin (VESIcare)fesoterodine (Toviaz)If you need to take Stiolto Respimat and a urinary incontinence medication such as the ones listed above, your doctor will monitor you closely. They’ll keep an eye out for increased side effects, such as eye problems or trouble urinating. They may also recommend a different COPD or urinary incontinence drug for you.

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