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Tremors Hallucinations Delusions And Seizures Are All Symptoms Associated With

Nuplazid can interact with several other medications. It can also interact with certain supplements as well as certain foods.Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe.Nuplazid and other medicationsBelow is a list of medications that can interact with Nuplazid. This list doesn’t contain all drugs that may interact with Nuplazid.Before taking Nuplazid, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.Nuplazid and certain heart medicationsNuplazid may interact with certain heart medications that prolong (lengthen) your QT interval. The QT interval is part of your heart rhythm, and if it becomes too long, it can lead to an irregular heart rate or rhythm.Nuplazid may prolong the QT interval. Therefore, taking it with heart medications that can also prolong the QT interval could raise your risk for this side effect even more.The type of heart medications that can prolong your QT interval are called antiarrhythmics. These drugs shouldn’t be taken with Nuplazid. Examples of antiarrhythmics include:quinidineprocainamidedisopyramide (Norpace)amiodarone (Pacerone)sotalol (Betapace)Before starting Nuplazid, talk with your doctor about any medications you’re taking. They can determine if these drugs may interact with Nuplazid.Nuplazid and certain antipsychoticsNuplazid shouldn’t be taken with certain antipsychotic medications that can prolong (lengthen) your QT interval. The QT interval is part of your heart rhythm, and if it becomes too long, it can cause an irregular heart rate or rhythm.Nuplazid may prolong the QT interval. Therefore, taking it with other medications that can also prolong the QT interval could raise your risk for this side effect even more.Examples of the antipsychotic drugs that shouldn’t be taken with Nuplazid include:ziprasidone (Geodon)chlorpromazinethioridazineIf you’re taking an antipsychotic medication, talk with your doctor. They can determine if the medication interacts with Nuplazid.Nuplazid and certain antibioticsNuplazid may interact with certain antibiotics that can prolong (lengthen) your QT interval. The QT interval is part of your heart rhythm, and if it becomes too long, it can cause an irregular heart rate or rhythm.Nuplazid may prolong the QT interval. Therefore, taking it with other medications that can also prolong the QT interval could raise your risk for this side effect even more.Examples of the antibiotics that may interact with Nuplazid include:gatifloxacin (Zymar)moxifloxacinIf you’re taking an antibiotic, talk with your doctor before starting Nuplazid. They can determine if your medication interacts with Nuplazid. Your doctor may recommend that you take a different antibiotic to treat your infection. They may also monitor your heart rhythm while you’re taking both drugs to make sure you don’t experience irregular heart rhythm.Nuplazid and CYP3A4 inhibitorsNuplazid may interact with medications that are CYP34A inhibitors.Nuplazid is broken down by a protein in your liver called CYP3A4. Other drugs, called CYP3A4 inhibitors, block this protein from working as it should. If CYP3A4 can’t properly break down Nuplazid, the amount of Nuplazid in your body can get too high. This may raise your risk for serious side effects.Examples of medications that are CYP3A4 inhibitors include:itraconazole (Tolsura, Sporanox)ketoconazole (Extina, Xolegel)clarithromycinindinavir (Crixivan)If you’re taking a medication that’s a CYP3A4 inhibitor, your doctor will likely lower your dose of Nuplazid. This can help prevent Nuplazid from building up in your body.Before starting Nuplazid, talk with your doctor about any medications you take. They can determine if the medications are CYP3A4 inhibitors, and if you’ll need to decrease your Nuplazid dosage.Nuplazid and CYP3A4 inducersYou shouldn’t take Nuplazid with medications that are CYP34A inducers.Nuplazid is broken down by a protein in your liver called CYP3A4. Other drugs, called CYP3A4 inducers, make this protein work faster than usual.If you take Nuplazid with a CYP3A4 inducer, your body will break down Nuplazid too quickly. This could lead to you not having enough Nuplazid in your body, which could make the drug less effective.Examples of medications that are CYP3A4 inducers include:modafinil (Provigil)carbamazepine (Tegretol)phenytoin (Dilantin)rifampin (Rifadin)thioridazineefavirenz (Sustiva)nafcillinTalk with your doctor or pharmacist about any medications you take before starting Nuplazid. They can determine if the medications are CYP3A4 inducers and if they’re safe to take with Nuplazid.Nuplazid and herbs and supplementsSt. John’s wort, a supplement that is often used for depression, may interact with Nuplazid. You shouldn’t take St. John’s wort during your Nuplazid treatment.Nuplazid is broken down by a protein in your liver called CYP3A4. St John’s wort is a CYP3A4 inducer, which means it makes this protein work faster than usual. Taking St. John’s wort with Nuplazid could make your body break down Nuplazid too quickly. This may make Nuplazid less effective.Before starting Nuplazid, talk with your doctor or pharmacist about any supplements or herbs that you’re taking. They can tell you if the supplements or herbs are safe to take with Nuplazid.Nuplazid and foodsNuplazid may interact with grapefruit. Therefore, you should avoid drinking grapefruit juice or eating grapefruit while taking Nuplazid.Nuplazid is broken down by a protein in your liver called CYP3A4. Grapefruit and grapefruit juice block this protein from working as it normally does. If CYP3A4 can’t properly break down Nuplazid, the amount of Nuplazid in your body can get too high. This may raise your risk for serious side effects.The manufacturer of Nuplazid doesn’t provide a specific recommendation about grapefruit. If you have questions about consuming grapefruit or grapefruit juice during your Nuplazid treatment, talk with your doctor.

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Psychosis, Delusions and Hallucinations – Psychiatry | Lecturio

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