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Astellas Patient Assistance Program Application Form For Myrbetriq

Myrbetriq can cause mild and serious side effects. The following lists contain some of the key side effects that may occur while taking Myrbetriq. These lists do not include all possible side effects.For more information about the possible side effects of Myrbetriq, talk with your doctor or pharmacist. They can give you tips on how to deal with any side effects that may be concerning or bothersome.Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. If you would like to notify the FDA about a side effect you’ve had with Myrbetriq, you can do so through MedWatch.Mild side effectsMild side effects* of Myrbetriq can include:* This is a partial list of mild side effects from Myrbetriq. To learn about other mild side effects, talk with your doctor or pharmacist, or view Myrbetriq’s patient information.† For more information about this side effect, see “Side effect details” below.Most of these side effects may go away within a few days or a couple of weeks. But if they become more severe or don’t go away, talk with your doctor or pharmacist.Serious side effectsSerious side effects from Myrbetriq aren’t common, but they can occur. Call your doctor right away if you have serious side effects. Call 911 or your local emergency number if your symptoms feel life threatening or if you think you’re having a medical emergency.Serious side effects and their symptoms can include:* For more information about this side effect, see “Side effect details” below.Side effects in childrenMyrbetriq is used to treat neurogenic detrusor overactivity (NDO) in children ages 3 years and older. NDO is an overactive bladder that’s caused by a nerve problem, such as spina bifida.In general, side effects of Myrbetriq in children are similar to those seen in adults. These are described above and below.But young children taking Myrbetriq may be more likely to have increased blood pressure than older children or adults taking this drug. In clinical studies, increased blood pressure was very common in children under 12 years old. See “Increased blood pressure” below to read more about this possible side effect of Myrbetriq.If you’re considering Myrbetriq as a treatment option for your child’s condition, talk with their doctor about possible side effects.Side effects in older peopleIn clinical studies, side effects of Myrbetriq reported in adults ages 65 years and older were similar to those seen in younger people.Certain other drugs used for overactive bladder (OAB) may cause troublesome side effects in older people. These drugs are called antimuscarinics (or anticholinergics). In particular, these drugs may increase the risk of dementia in older people.Myrbetriq isn’t an antimuscarinic drug. It’s not associated with this side effect. And it’s not known to cause more side effects in older people than in younger people.Side effect detailsHere’s some detail on certain side effects this drug may cause.DiarrheaMyrbetriq can sometimes cause diarrhea, although it’s not common. Myrbetriq is more likely to cause constipation, particularly if it’s taken with solifenacin (Vesicare).Diarrhea wasn’t specifically reported in children who took Myrbetriq in clinical studies. But gastroenteritis was reported in some children. Gastroenteritis is a stomach infection that can cause diarrhea.With diarrhea, you pass loose or watery stools. Or you may need to pass stools urgently or more frequently than usual.To find out how often diarrhea occurred with Myrbetriq in clinical studies, see the drug’s prescribing information.What you can doIf you have diarrhea with Myrbetriq, this can make you lose more fluids than usual. Be sure to drink plenty of fluids to avoid getting dehydrated. Taking an oral rehydration solution such as Pedialyte can also help replace lost fluids and electrolytes.If you have diarrhea that’s troublesome or lasts longer than a few days, talk with your doctor. They may recommend medication to help stop the diarrhea.Contact your doctor right away if you have blood in your stools or symptoms of dehydration. These may include dry mouth, thirst, dark urine, and decreased urine production. Your doctor may need to prescribe other treatments for these problems.Kidney problemsMyrbetriq doesn’t directly cause kidney problems. It can cause UTIs and urinary retention (being unable to empty your bladder). These side effects can sometimes lead to kidney problems.To find out how often UTIs and urinary retention occurred with Myrbetriq in clinical studies, see the drug’s prescribing information.UTIsMyrbetriq may cause UTIs in some people. This was one of the most common side effects reported by people who took Myrbetriq in clinical studies. UTIs usually involve the lower urinary tract (urethra and bladder). But more rarely, they can spread into the upper urinary tract (ureters and kidneys). A kidney infection is a serious condition that can lead to sepsis (blood poisoning).Symptoms of UTIs can include:burning sensation when urinatingurinating more often than usualpassing urine that’s cloudy, dark brown, or contains blood (this may look pink)pelvic pain in females*rectal pain in males*feverchillsnausea and vomitingpain in the upper back or sides* Sex and gender exist on spectrums. Use of the terms “male” and “female” in this article refers to sex assigned at birth.What you can doIf you have symptoms of a UTI while you’re taking Myrbetriq, contact your doctor right away. They’ll likely prescribe antibiotic medication to treat the infection. You might also try drinking plenty of fluids to help flush any bacteria out of your urinary tract.To help prevent UTIs, it may be useful to drink cranberry juice on a regular basis.Urinary retentionSome people may experience urinary retention while using Myrbetriq. But this wasn’t a common side effect in clinical studies with Myrbetriq. It’s more likely to occur in people with a bladder outlet obstruction (a condition that makes it hard for urine to flow out of your bladder, such as an enlarged prostate). It’s also more likely to occur in people taking an antimuscarinic drug such as solifenacin (Vesicare).If urinary retention isn’t treated, it can increase the pressure in the urinary tract and damage the kidneys.Symptoms of urinary retention can include:trouble starting to urinateweak urine streamleaking urineneeding to urinate again right after you’ve finished urinatingdiscomfort or feeling of fullness in your bladderWhat you can doIf you have symptoms of urinary retention while taking Myrbetriq, contact your doctor right away. They may need to place a catheter (tube) into your bladder to release the urine.Increased blood pressureMyrbetriq can sometimes cause increased blood pressure.In clinical studies, this was one of the most common side effects reported in adults who took Myrbetriq on its own. (Even so, most people taking the drug on its own didn’t have this side effect.)Increased blood pressure wasn’t reported in adults who took Myrbetriq with solifenacin (Vesicare). And it wasn’t reported in children over 12 years old. But in children under 12 years old, this side effect was very commonly reported.To find out how increased blood pressure occurred with Myrbetriq in clinical studies, see the drug’s prescribing information.A small increase in blood pressure doesn’t usually cause a problem. But if blood pressure increases too much, it can raise the risk of heart attack and stroke.What you can doHigh blood pressure doesn’t usually have any symptoms. Your doctor will monitor your blood pressure on a regular basis to make sure Myrbetriq isn’t causing any problems.If your blood pressure increases too much with this drug, your doctor may prescribe medication to help lower it. Or they may recommend switching to a different treatment for your bladder problem.Allergic reactionAs with most drugs, some people can have an allergic reaction after taking Myrbetriq.Symptoms of a mild allergic reaction can include:rashitchinessflushing (temporary warmth, redness, or deepening of skin color)A more severe allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include:swelling under your skin, typically in your eyelids, lips, hands, or feetswelling of your tongue, mouth, or throattrouble breathingCall your doctor right away if you have an allergic reaction to Myrbetriq, as the reaction could become severe. Call 911 or your local emergency number if your symptoms feel life threatening or if you think you’re having a medical emergency.

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